How Can We Help You?

There may be options to help you afford RITUXAN HYCELA, no matter what type of health insurance you have.

Referrals to Independent Co-pay Assistance Foundations

If you need help with the co-pay for RITUXAN HYCELA, Genentech BioOncology Access Solutions can refer you to an independent co-pay assistance foundation.

An independent co-pay assistance foundation is a charitable organization that gives financial assistance for medicines.

Call Genentech BioOncology Access Solutions at (888) 249-4918 for a referral.

If you would like to contact a foundation directly, you can use the information below:

CancerCare Co-Payment Assistance Foundation
275 Seventh Avenue, 22nd Floor
New York, NY 10001
Toll Free: 1-866-55-COPAY (866-552-6729)

The HealthWell Foundation
P.O. Box 220410
Chantilly, VA 20153-0410
Toll Free: 1-800-675-8416

Patient Access Network Foundation (PANF)
P.O. Box 221858
Charlotte, NC 28222-1858
Toll Free: 1-866-316-PANF (7263)

The Assistance Fund, Inc.
4700 Millenia Boulevard, Suite 410
Orlando, FL 32839
Toll Free: 1-855-845-3663

The Leukemia and Lymphoma Society
1311 Mamaroneck Avenue, Suite 310
White Plains, NY 10605
Toll Free: 1-877-557-2672 (877-LLS-COPAY)

Independent co-pay assistance foundations have their own rules for eligibility. We cannot guarantee a foundation will help you. We only can refer you to a foundation that supports your disease state. This information is provided as a resource for you. We do not endorse or show financial preference for any particular foundation. The foundations in this list are not the only ones that might be able to help you.

Referrals to the Genentech Patient Foundation

The Genentech® Access to Care Foundation is now the Genentech Patient Foundation.

We are still focused on giving free medicines to patients in need, but we've made some changes to provide better support to more patients, more quickly.

The Genentech Patient Foundation provides free medicines to people:

  • Who don't have insurance
  • Whose treatment is not covered by insurance
  • Who are struggling with high out-of-pocket costs

To learn more and to apply for help, visit

If you have health insurance coverage for your medicine, you must have already tried other types of patient assistance to qualify for free RITUXAN HYCELA from the Genentech Patient Foundation. This includes the Genentech BioOncology Co-pay Card and support from independent co-pay assistance foundations. You must also meet financial criteria. If you do not have insurance or your insurance does not cover your medicine, you must meet different financial criteria.

Referrals to the Genentech BioOncology Co-pay Card

Genentech BioOncology Access Solutions can refer you to the Genentech BioOncology Co-pay Card. It can help you with the out-of-pocket costs for RITUXAN HYCELA, if you’re eligible.

The Genentech BioOncology Co-pay Card helps patients with commercial health insurance. This might be a plan you get through your employer or one you purchased through a Health Insurance Marketplace like To qualify, you must also meet other criteria.

In order to be eligible for the Genentech BioOncology Co-pay Card, the patient must have commercial insurance, must not have Medicare, Medicaid or other government insurance, and must meet other eligibility criteria. They also must agree to the rules set forth in the terms and conditions for the program. Please visit for the full list of terms and conditions.

How to Work With Genentech BioOncology® Access Solutions

Step 1

Enroll in Genentech BioOncology Access Solutions.

How do I enroll?

Step 2

We work with you, your doctor’s office, your health insurance plan and your specialty pharmacy. We might contact you for more information.

What will we find out?

Step 3

We refer you to patient assistance options.

What options are there?

Important Safety Information & Indication

What it Treats


RITUXAN HYCELA® (rituximab/hyaluronidase human) is a prescription medicine used to treat adults with:

  • Follicular Lymphoma (FL) as a single-agent therapy in patients whose disease recurred or did not respond to initial treatment
  • Follicular Lymphoma as an initial treatment with chemotherapy and, in patients whose initial treatment was successful, as a single-agent follow-up therapy
  • Follicular Lymphoma as a single agent follow-up therapy for patients who did not progress on initial treatment with CVP chemotherapy
  • Diffuse Large B-Cell Lymphoma (DLBCL) as an initial treatment in combination with CHOP or other anthracycline-based chemotherapy regimens
  • Chronic Lymphocytic Leukemia (CLL) in combination with FC chemotherapy as an initial treatment or as a treatment after disease has recurred

You can only receive RITUXAN HYCELA after you receive at least 1 full dose of intravenous (IV) RITUXAN® (rituximab). Read the IV RITUXAN Medication Guide for more information about severe infusion reactions, which usually happen during the first dose with IV RITUXAN.

RITUXAN HYCELA is not for use to treat medical conditions other than cancers.

It is not known if RITUXAN HYCELA is safe and effective in children.

Important Safety Information

What is the most important information I should know about RITUXAN HYCELA?

RITUXAN HYCELA can cause serious side effects that can lead to death, including:

  • Severe skin and mouth reactions: Tell your healthcare provider or get medical help right away if you get any of these symptoms at any time during your treatment with RITUXAN HYCELA: painful sores or ulcers on your skin, lips, or in your mouth; blisters; peeling skin; rash or pustules.
  • Hepatitis B virus (HBV) reactivation: Before you receive RITUXAN HYCELA, your doctor will do blood tests to check for HBV infection. If you have had hepatitis B or are a carrier of hepatitis B virus, receiving RITUXAN HYCELA could cause the virus to become an active infection again. Hepatitis B reactivation may cause serious liver problems including liver failure and death. Your healthcare provider will monitor you for hepatitis B infection during and for several months after you stop receiving RITUXAN HYCELA. Tell your healthcare provider right away if you get worsening tiredness, or yellowing of your skin or white part of your eyes during treatment with RITUXAN HYCELA.
  • Progressive Multifocal Leukoencephalopathy (PML): PML is a rare, serious brain infection caused by a virus that can happen in people who receive RITUXAN HYCELA. People with weakened immune systems can get PML. PML can result in death or severe disability. There is no known treatment, prevention, or cure for PML. Tell your healthcare provider right away if you have any new or worsening symptoms or if anyone close to you notices these symptoms: confusion; dizziness or loss of balance; difficulty walking or talking; decreased strength or weakness on one side of your body; vision problems, such as blurred or loss of vision.
  • Serious allergic reactions and other severe reactions:
    Serious allergic reactions, and reactions due to release of certain substances by the body that can lead to death, can happen with rituximab products, including RITUXAN HYCELA.

Skin reactions at or near the injection site (local), including injection site reactions can happen with RITUXAN HYCELA. Symptoms at or near the injection site may include: pain, swelling, hardness, redness, bleeding, itching, and rash. These reactions sometimes happen more than 24 hours after an injection of RITUXAN HYCELA.

Tell your healthcare provider or get medical help right away if you get any of these symptoms during or after an injection of RITUXAN HYCELA: hives (red itchy welts) or rash; itching; swelling of your lips, tongue, throat, or face; sudden cough; shortness of breath, difficulty breathing, or wheezing; weakness; dizziness or feeling faint; palpitations (feeling like your heart is racing or fluttering); chest pain; fever; chills or shaking chills.

What are possible side effects of RITUXAN HYCELA?

RITUXAN HYCELA can cause serious side effects, including:

  • Tumor Lysis Syndrome (TLS): TLS is caused by the fast breakdown of cancer cells. TLS can cause you to have kidney failure, the need for dialysis treatment, and an abnormal heart rhythm. TLS can happen within 12 to 24 hours after an injection of RITUXAN HYCELA. Your healthcare provider may do blood tests to check you for TLS. Your healthcare provider may give you medicine to help prevent TLS. Tell your healthcare provider right away if you have any of the following signs or symptoms of TLS: nausea, vomiting, diarrhea, or lack of energy.
  • Serious Infections: Serious infections can happen during and after treatment with RITUXAN HYCELA and can lead to death. Rituximab products can increase your risk of getting infections and can lower the ability of your immune system to fight infections. Types of serious infections that can happen with RITUXAN HYCELA include bacterial, fungal, and viral infections. After receiving RITUXAN HYCELA, some people have developed low levels of certain antibodies in their blood for a long period of time (longer than 11 months). Some of these people with low antibody levels developed infections. Tell your healthcare provider right away if you have any symptoms of infection: fever; cold symptoms, such as runny nose or sore throat that do not go away; flu symptoms, such as cough, tiredness, and body aches; earache or headache; pain during urination; white patches in the mouth or throat; cuts, scrapes, or incisions that are red, warm, swollen, or painful.
  • Heart Problems: RITUXAN HYCELA may cause chest pain, irregular heartbeats, and heart attack. Your healthcare provider may monitor your heart during and after treatment with RITUXAN HYCELA if you have symptoms of heart problems or have a history of heart problems. Tell your healthcare provider right away if you have chest pain or irregular heartbeats during treatment with RITUXAN HYCELA.
  • Kidney Problems: RITUXAN HYCELA can cause severe kidney problems that can lead to death. Your healthcare provider should do blood tests to check how well your kidneys are working.
  • Stomach and serious bowel problems that can sometimes lead to death: Bowel problems, including blockage or tears in the bowel, can happen if you receive RITUXAN HYCELA with chemotherapy medicines. Tell your healthcare provider right away if you have severe stomach-area (abdomen) pain or repeated vomiting during treatment with RITUXAN HYCELA.

Your healthcare provider will stop treatment with RITUXAN HYCELA if you have severe, serious, or life-threatening side effects.

The most common side effects of RITUXAN HYCELA in people with:

  • FL: infections, low white blood cell count, nausea, constipation, cough, and tiredness.
  • DLBCL: infections, low white blood cell count, loss of hair, nausea, and low red blood cell count.
  • CLL: infections, low white blood cell count, nausea, low platelet count, fever, vomiting, and injection site redness.

Additional Important Safety Information

Before receiving RITUXAN HYCELA, tell your healthcare provider about all of your medical conditions, including if you:

  • Have had a severe reaction to a rituximab product or RITUXAN HYCELA.
  • Have had a recent vaccination or are scheduled to receive vaccinations. You should not receive certain vaccines before or during treatment with RITUXAN HYCELA.
  • Are pregnant, plan to become pregnant, are breastfeeding, or plan to breastfeed. Talk to your healthcare provider about the risks to your unborn baby if you receive RITUXAN HYCELA during pregnancy. Females who are able to become pregnant should use effective birth control (contraception) during treatment with RITUXAN HYCELA and for 12 months after the last dose of RITUXAN HYCELA. Talk with your healthcare provider about effective birth control. It is not known if RITUXAN HYCELA passes into your breast milk. Do not breastfeed during treatment and for at least 6 months after your last dose of RITUXAN HYCELA.

These are not all of the possible side effects with RITUXAN HYCELA. Call your doctor for medical advice about side effects.

Please see the full Prescribing Information, including BOXED WARNINGS and Medication Guide, for additional Important Safety Information.

You may report side effects to the FDA at (800) FDA-1088 or You may also report side effects to Genentech at (888) 835-2555.