Buy And Bill

“Buy and bill” is a term used by health care providers when an office or facility purchases ACTEMRA for intravenous (IV) infusion, then bills an insurer for reimbursement. Once the bill is submitted, your office is reimbursed for the product. With buy and bill, you can maintain a stock of ACTEMRA IV, giving you the flexibility to treat your patients when clinically appropriate.

Specialty Pharmacies

Specialty pharmacies (SPs) can dispense ACTEMRA to your office. For the subcutaneous (SC) formulation of ACTEMRA, SPs may also be able to dispense directly to your patients. The SPs can also provide coverage and reimbursement support. We work with these SPs to make patient and clinical support available to ACTEMRA patients and their prescribers.

An SP is uniquely able to give a comprehensive array of services. They include:

• Reimbursement resources
• Clinical services to support patients throughout their therapies
• The ability to manage special handling and shipping needs linked with many specialty therapies

The decision to use the services of an SP should be made solely by patients and their caregivers with guidance from the provider/treatment team.

Genentech does not make any representation or guarantee concerning any service or item offered by an SP.

Spoilage Replacement Program

If the ACTEMRA prescribed for a labeled indication was spoiled and unable to be administered, the product might be eligible for replacement through the Genentech Spoilage Replacement Program.*

Patients who need replacement product for ACTEMRA for subcutaneous (SC) injection should contact their specialty pharmacy.

For more information, please contact (800) ACTEMRA (800-228-3672)

Potential reasons for replacement

ACTEMRA has been reconstituted and is unusable due to one of the following events:

• Product was reconstituted and patient missed appointment
• Product was accidentally dropped
• Product was not appropriately refrigerated or was frozen
• Patient expired/coded
• Product was not administered due to unforeseen symptoms

For all quality- or stability-related issues, please contact Genentech Medical Communications at (800) 821-8590.

For expired product returns, please contact Genentech Customer Operations at (800) 551-2231.

For questions about spoiled ACTEMRA SC, please call (800) ACTEMRA (800-228-3672).

Product replacement procedure

To request replacement product:

1. Contact Genentech Customer Operations at (800) 551-2231 to obtain the Genentech Spoilage Replacement Program form.
2. Complete the Genentech Spoilage Replacement Program form. Please write legibly and fill in ALL required fields to prevent delays.
3. Fax the form to (877) 329-6737.
4. The request might take up to 3 business days to review. If approved, instructions for how to return the spoiled product or verify spoilage are provided at this time.
5. Replacement product ships within 11 business days following receipt of the spoiled product or Certification of Destruction form (provided by Customer Operations).

Please be sure to retain all intact vials. Unless the vial(s) is broken, all products must be returned. If the vial(s) is broken, a completed Certification of Destruction form is required.

*Subject to certain limitations and conditions. The Spoilage Replacement Program covers infused or injected Genentech products. Genentech has the right to modify or discontinue the Spoilage Replacement Program at any time without notice.