Learn About Our Services

Genentech BioOncology® Access Solutions for COTELLIC and ZELBORAF is your resource for access and reimbursement support after COTELLIC and ZELBORAF are prescribed.

Coverage

Help understanding benefits and coverage, such as benefits investigations and prior authorization resources

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Reimbursement

Sample coding information and resources for denials and appeals

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Product Distribution

A list of authorized distributors and specialty pharmacies

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Online Patient Enrollment

Submit Genentech BioOncology Access Solutions forms and check the status of your service requests online using My Patient Solutions

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Our Commitment to Patients

Over the past 20+ years,
Genentech has helped more than

1.7 million

patients access the Genentech medicines they need.

In 2017, we helped more than

227,000

patients access the Genentech medicines they need.

Communication assistance services

Genentech BioOncology Access Solutions employs a multilingual call center staff and offers teletypewriter (TTY) services for callers.
 

PAN=Patient Authorization and Notice of Request for Transmission of Health Information to Genentech Access Solutions and Genentech® Access to Care Foundation.

Important Safety Information & Indication

Indication

COTELLIC (cobimetinib) is indicated for the treatment of patients with unresectable or metastatic melanoma with a BRAF V600E or V600K mutation, in combination with ZELBORAF (vemurafenib).

Important Safety Information

WARNINGS AND PRECAUTIONS

Review the Full Prescribing Information for ZELBORAF for information on the serious risks of ZELBORAF.

The following can occur in patients treated with COTELLIC:

  • New primary malignancies, including cutaneous and non-cutaneous malignancies
  • Hemorrhage, including major hemorrhages
  • Cardiomyopathy, defined as symptomatic and asymptomatic decline in left ventricular ejection fraction
  • Severe dermatologic reactions, including rash and other skin reactions
  • Serous retinopathy and retinal vein occlusion
  • Hepatotoxicity
  • Rhabdomyolysis
  • Severe photosensitivity
  • Embryo-fetal toxicity

USE IN SPECIFIC POPULATIONS: Lactation

Do not breastfeed while taking COTELLIC and for 2 weeks after the final dose.

DRUG INTERACTIONS

Avoid concomitant administration of COTELLIC with strong or moderate CYP3A inducers or inhibitors.

Most Common Adverse Reactions

The most common (≥20%) adverse reactions with COTELLIC were diarrhea (60%), photosensitivity reaction (46%), nausea (41%), pyrexia (28%), and vomiting (24%). The most common (≥5%) Grade 3-4 laboratory abnormalities were increased GGT (21%), increased CPK (14%), hypophosphatemia (12%), increased ALT (11%), lymphopenia (10%), increased AST (8%), increased alkaline phosphatase (7%), and hyponatremia (6%).

You may report side effects to the FDA at (800) FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at (888) 835-2555.

Please see Full COTELLIC Prescribing Information for additional Important Safety Information.